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In a randomized, double-blind study, liraglutide was found to be more effective than a placebo group for weight loss in obese adults with type 2 diabetes

It impairs judgment , affecting decision-making and risk assessment

Overall, the effect of GLP-1RAs on muscle mass shows a high degree of heterogeneity in clinical trials: some studies report that lean body mass reduction accounts for 40% to 60% of total weight loss, while others indicate that the proportion of lean body mass reduction is approximately 15% or lower [50]

Patients who titrate gradually from 2.5mg often achieve the same or better long-term results than those pushing to higher doses quickly, because they stick with the medication and find their optimal dose without discontinuing due to side effects

20.32%, not significant)