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There is increasing interest in whether and how GLP-1 medicines impact adipose tissue, muscle, and bone, questions with important clinical implications, especially in individuals who may be frail and experiencing rapid and substantial weight loss
Compared to patients with minimal or moderate response, super responders were more likely to be younger (mean age 51years versus 55years), female (80% versus 58-65%), and white (90% versus 80%)

We subsequently developed an in vivo technique to assess gut hormone release into the portal vein following colonic infusion of propionate

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