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Clinical outcomes with canagliflozin according to baseline body mass index: results from post hoc analyses of the CANVAS program

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Its target is for a subset of individuals who have severe obesity due to genetic variants that impair the melanocortin-4 receptor (MC4R) pathway, a pathway in the brain that is responsible for regulating hunger, caloric intake, and energy expenditure, which consequently affect body weight

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Available from: Dong N, Zhu C, Jiang J, Huang D, Li X, Quan G, et al

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That sounds dramatic, but it is biologically accurate

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