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The medication is metabolised through proteolytic degradation rather than hepatic cytochrome P450 enzymes, which are the primary pathways affected by alcohol metabolism

2.4 Assessments Safety assessments included AEs, hypoglycaemic episodes, laboratory safety parameters, physical examination, vital signs and electrocardiogram

doi: 10.1192/bjo.2024.841

Therefore, we have heated the mimic MNs formulation and control samples (using PBS as a diluent) at extremely high temperature (80 C for 1h)

Data analysis occurred from March to April 2023, with additional analysis in February 2024

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