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People who have plateaued on other GLP-1 medications If semaglutide stopped working or never produced adequate results, tirzepatide dual mechanism offers a different pharmacological approach

Nausea is already the most commonly reported side effect of oral semaglutide in clinical trials, particularly in the first month of treatment. Alcohol irritates the stomach lining, and on a gut that's already adjusting to slowed gastric emptying, it's a reliable way to make nausea significantly worse

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Your tolerance may be significantly lower than it was before you started the medication, so what used to be a normal amount of alcohol could now be too much