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This is expected and does not necessarily indicate a problem, but monitoring during the transition is important

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Lean ME, Powrie JK, Anderson AS, et al

Low testosterone promotes fat accumulation, reduces muscle mass, and decreases metabolic rate

Tirzepatide: A novel cardiovascular protective agent in type 2 diabetes mellitus and obesity

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GLP-1 receptor agonists act on a single incretin pathwaythe GLP-1 pathwayto regulate blood sugar and appetite
