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Balk E.M., Cooney T.G., Cross J.T., Jr., et al

Each vial should be inspected visually before each use for any signs of particulate matter, discoloration, cloudiness, or other changes in appearance

Meal timing, portion size, and posture after eating are the most effective first steps

Following the dose-escalation schedule in the product SmPC is important to minimise these effects, and several practical strategies can help manage digestive symptoms effectively

Economically it can also have a major impact

The American College of Gastroenterology regards it as a frontline defense against symptoms like constipation
