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Thyroid cancer The prescribing information for GLP-1RA lists MTC as a contraindication, based on a preclinical rodent study demonstrating that GLP-1R activation elevates cAMP levels in rodent thyroid C-cells, stimulates calcitonin release, and promotes C-cell hyperplasia and MTC development (200)
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Beyond the stomach and brain, GLP-1 receptors are also found in the kidneys, which is why researchers have spent significant time studying how these medications impact renal function
Always follow the patient leaflet or guidance from a healthcare professional
The research studies didn't specify food timing, suggesting flexibility in administration
No matter what happens, give yourself grace, Adair emphasizes
