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high discontinuation rates (e.g., 50-67% at 1 year and 85% at 2 years 5-8 ) that may relate to side effects, costs, variable individual efficacy, or patient preferences 5,9

In 2005, the FDA approved the use of GLP-1 RAs in the form of a twice-daily injection for adults with type 2 Diabetes

Thereafter, ongoing vigilant oversight of process performance and product quality are necessary to ensure you maintain a stable manufacturing operation throughout the product lifecycle. 27 Regulations 21 CFR 211.84(d)(1) and 211.84(d)(2) remain a top citation in warning letters, and the agency continues to focus on risk of substitution or sub- or super-potent ingredients in OTC products like hand sanitizer

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GLP-1 agonists are a group of medications that help to manage blood sugar in people with Type 2 diabetes, some of which can be used to treat obesity even in people who do not have diabetes

Work with your healthcare provider to adjust meal-time insulin doses and timing when starting or adjusting a GLP-1 agonist