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Description
Discussion We successfully switched an acromegaly patient with pasireotide-induced deterioration of glycemic control from a DPP-4 inhibitor to a GLP-1 analog

Give it at least 3 months
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In one study, intact GLP-1 [(736)NH 2 ] (measured using the sandwich ELISA from Linco Research, St Charles, MO, USA) concentrations of approximately 30 pmol/l peaked around 15 min after oral stimulation [31], strongly contrasting to the levels obtained by others [32,33,34,35] using sandwich ELISA techniques (which usually measure concentrations around 0 pmol/l), raising doubts as to the validity of this measurement

The authors acknowledge that the science is unclear if one should calculate protein requirements using actual body weight or adjusted body weight for people living with obesity

D., Stierman, B., & Ogden, C