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However, as DPP4 recognizes other substrates such as chemokines, growth factors and neuropeptides, pleiotropic effects have been observed in patients treated with DPP4i

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The current therapy associated with repeated subcutaneous injections to maintain the drug therapeutic effect causes patient compliance issues ...

Heroin dependence reduces glutamatergic neurons in BLA without affecting anxiety and depression-like behaviors, due to the inhibitory effect of heroin reward

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