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Cochrane Database Syst Rev 2015;3:CD:010743

The incidence of nausea was as follows: placebo: 7.7%

Losing over three pounds per week (considered rapid weight loss) causes the liver to secrete extra cholesterol into bile, which can cause gallstones

The study is published in the journal Cell Metabolism

T2DM patients also see an abundance of free FAs in the plasma, which reduces insulin-regulated glucose metabolism [27]