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Gradual change is often easier to maintain than fast extremes
[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Scilletta S., Di Marco M., Miano N., Filippello A., Di Mauro S., Scamporrino A., Musmeci M., Coppolino G., Di Giacomo Barbagallo F., Bosco G., et al

You are experiencing difficulty controlling your blood sugar levels after switching medications, or if you notice symptoms such as excessive thirst, frequent urination, fatigue, or unexplained weight loss

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d) condensing Fmoc-Thr(tBu)-Phe-Thr(tBu)-Ser(tBu)-Asp(OtBu)-Val-Ser(Oxa)-OH (fragment-2) with 20 amino acid peptide chain obtained in step-c) in presence of a coupling agent followed by deprotection in presence of a base to obtain 27 amino acid peptide chain
