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2019 Apr 16;321(15):1466-1480
Emerging evidence supports that metabolic changes can influence reproductive hormones
Understanding the timeline of tirzepatide effects helps plan around medical events

Bottom line: last week's record is what makes this week's shot easy, instead of starting from a guess

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As the new obesity pharmacotherapies will lead up to 1525% mean WL, intensive lifestyle interventions may provide small additional WL benefit to these treatments [11, 106]