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The effectiveness of its GIP receptor antagonism is still under investigation

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The present research systematically evaluates the impact of bariatric surgery on appetite modulation and certain metabolic functions through key signaling pathways, including GLP-1R, GHS-R1a, and FXR/TGR5.

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In published research it has been investigated for its effects on body composition, glycaemic control, hepatic lipid metabolism and energy expenditure