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Interestingly, release of GLP1 specifically into the ventricles has been suggested as a means of reaching hippocampal GLP1 receptors in the hippocampus, an area that lacks PPG neuron axon terminals (Hsu et al., 2015
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Because Wegovy has a 7-day half-life, the extra medication from the double dose is still active in your system a week later
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Leptin receptorexpressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice
