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2010;59(Suppl

Ottman, N., et al., Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

JAMA Network Open, 9(1), e2555952

However, when exenatide's action was blocked, their brain responses and eating behavior resembled those in the placebo condition

The Accelerated Approval is based on part 1 of the ESSENCE trial that showed that at 72 weeks, 36.8% of people treated with Wegovy 2.4 mg achieved improvement in liver fibrosis with no worsening of steatohepatitis compared to 22.4% of individuals who received placebo

While we still need more data, I think GLP-1s deserve a place in the conversation for patients with PCOS, insulin resistance, or obesity who are struggling to conceive.
