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13 While GLP-1 agonist-induced weight loss can decrease mechanical load through the musculoskeletal system and improve aspects of physical function, the resulting negative effects on tendons, impaired muscle function, and joint degradation can persist after a healthy weight has been achieved

Krugh M et al
Orlistat, which works by reducing fat absorption rather than suppressing appetite, may carry different risk profiles, though it can cause gastrointestinal side effects

dumbbells, barbells), resistance bands, or even body weight (e.g

This is the conversation worth having with your physician

Different medication forms such as semaglutide versus tirzepatide could result in different nutrient intakes