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There are several different GLP-1 medications currently approved for weight loss in people with obesity, including: Liraglutide and semaglutide are GLP-1 receptor agonist medications, while tirzepatide is a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist medication

However, tirzepatide already holds FDA approval specifically for type 2 diabetes (Mounjaro), and its glycemic efficacy data is incredibly robust

The roles of GLP-1 with regard to actin dynamics in cardiovascular and neurodegenerative disease processes have not yet been well established

Furthermore, providers should educate patients on sustainable nutritional practices , emphasizing diets rich in protein, fiber, healthy fats, and low glycemic-index carbohydrates

From this point of view, the weight loss effect of SGLT2is, although considered modest and below the clinical significance of 5% overall, has the potential to become the anchor for our efforts to shift the perspective of patients toward healthy behaviors and adherence to treatment

The groups that oversee compounding in the US, the Alliance for Pharmacy Compounding and the Outsourcing Facilities Association, told Business Insider that anyone getting retatrutide from a clinic or a lab should know that it is not compounded or regulated