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In these studies, the authors did not measure plasma DPP4 activity, so it is not known whether the lower blood glucose was caused by inhibition of DPP4 activity

Little work has previously been undertaken to evaluate safety with long-term efficacy and cardio-renal benefits of such therapies

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[DOI] [PubMed] [Google Scholar] 65.Willms B, Werner J, Holst JJ, Orskov C, Creutzfeldt W, Nauck MA

GLP-1 Receptor Agonists and Cardiometabolic Effects

(Survey conducted by Pendulum.) (*These statements have not been evaluated by the Food and Drug Administration