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Insulin resistance (IR) occurs early in the course of PCOS and is frequently present even in the absence of obesity, accounting for 60-80% of women with PCOS (26)

Elevated levels may signal impaired glucose tolerance or diabetes, which influences starting dosages and monitoring requirements

SGLT-2 inhibitor and GLP-1 receptor agonist treatment for patients with nonalcoholic fatty liver disease and type 2 diabetes mellitus: is their combination the optimal treatment option

Those who took a GLP-1 had a lower risk of complications, including progression to proliferative diabetic retinopathy, diabetic macular edema, vitreous hemorrhage, and neovascular glaucoma

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