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3.1 Clinical trial landscape: observations on effect size and heterogeneity Currently, RCTs of GLP-1RAs in PCOS are generally characterized by small sample sizes, single-center designs, and relatively short follow-up periods

Occasionally, GLP-1s affect intestinal motility or secretions, contributing to diarrhea [44]

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The treatment is administered to reduce the risk of major cardiovascular events (cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) in adults with type 2 diabetes who were confirmed with cardiovascular disease

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