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This happens because your skin stretches to accommodate the extra fat, and over time, the fibres that keep it firm and stretchycollagen and elastincan get worn out or damaged

Tirzepatide in Renal Function and Outcomes Tirzepatide was associated with a significantly greater reduction in the urine albumintocreatinine ratio (UACR) compared with controls, with an average decrease of approximately 26.9%

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Exercise, particularly resistance training, is crucial for preserving lean mass and functional health, especially during weight loss (11, 17, 18)

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Managing gastrointestinal side effects: Tirzepatide can sometimes cause nausea or stomach discomfort, especially when initiating or increasing your dose