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As of early 2026, only 13 state Medicaid programs cover GLP-1 medications for weight loss, down from 17 states at the start of the year California, New Hampshire, Pennsylvania, and South Carolina dropped coverage on January 1, 2026, citing budgetary constraints from the high cost of medications like Ozempic, Wegovy, and Zepbound

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Long-term semaglutide use for weight management shows generally favorable safety data in clinical trials, though individual outcomes depend on baseline health status, existing conditions, and genetic predispositions

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