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Heart failure is a common complication of obesity [61, 62], and clinical trials have shown that GLP-1 analogs, particularly tirzepatide, can improve cardiac function and reduce the risk of heart failure in people with obesity [63]

This allows for appropriate risk assessment and implementation of safety measures to minimize aspiration risk while maintaining glycemic control throughout the perioperative period

What gets combined with it, and why, can shift the entire trajectory of a weight loss protocol

Mounjaro (tirzepatide) side effects & how to treat them Written by: Thomas Kolbe-Booysen , 17 Feb 2026 28 min read Reviewed and fact-checked: Mounjaro can cause side effects, especially when you first start or increase your dose

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Do females experience different side effects with tirzepatide and semaglutide