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The increased energy expenditure from glucagon receptor activation means your total daily expenditure is higher than it was on tirzepatide at equivalent body weight

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Mitchell et al

Block ML, Hong J-S

By addressing multiple pathophysiological pathways, including insulin resistance, inflammation, and oxidative stress, Tirzepatide presents a unique opportunity to redefine treatment paradigms beyond glycemic management

Beyond working with a doctor to ensure nutritional benchmarks are met, the recommendations include screening for a history of disordered eating and taking into account a persons whole health before prescribing
