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Some observational studies of patients with type 2 diabetes suggest that GLP-1 receptor agonist use associates with reduced dementia risk compared with other glucose-lowering medications, but these findings require cautious interpretation due to potential confounding factors

Nonetheless, the role of PPAR in regulating food intake remains controversial, since studies have shown discrepant results depending on the models used and experimental conditions 10,11,23

( / mice on high-fat diet

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Studies of human adipose tissue in vivo