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A thorough pre-treatment conversation with your provider should address expected side effects (nausea, constipation, potential thyroid considerations), timeline to effect, and realistic expectations around weight loss or metabolic improvementtypically 510% body weight reduction in clinical trials

Due to patent protection, earlier it was marketed globally only by the innovator company under brand names like Ozempic, Wegovy, and Rybelsus, which made therapy expensive and limited its accessibility for many patients in India

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If you've been in a 500-calorie daily deficit for several months, your metabolic adaptation may require you to either reduce intake further or increase activity levels

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