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M., Gratzl S., et al., Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity, JAMA Internal Medicine 184 (2024): 1056, 10.1001/jamainternmed.2024.2525

Clinical data from the TIPO-1 trial and community experience form the basis of the protocols documented below
Weight loss diet with a target 12001500 kcal/d for women and 15001800 kcal/d for men is recommended to achieve weight loss of at least 510% in patients with HF and obesity [15, 16]
The second, Wegovy, was approved for weight loss in June 2021 under the same BMI guidelines as Saxenda

Platforms operating within current regulatory frameworks may face changing requirements as regulations evolve
