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This provision fundamentally transforms the role of the 503B from a niche provider of customized medications to a sanctioned, large-scale source of supply during a public health need

Wu YH, Swaab DF

People who used SGLT2i at baseline were younger, less frequently female, had lower systolic blood pressure, and higher eGFR

In people without diabetes Weight loss was greater : ~8 kg at 12 mg ~12 kg at 36 mg At higher doses, participants were: ~14 more likely to achieve 10% weight loss ~15 more likely to reach 15% weight loss This aligns with whats been seen with injectable GLP-1sbut now via an oral agent

Similarly, another retrospective analysis of 886 patients undergoing elective upper endoscopy demonstrated that semaglutide was associated with not only increased residual gastric content but also that digestive symptoms prior to the procedure were also predictive of this outcome

Clinical studies have shown that Mounjaro can lead to significant weight loss for individuals with obesity