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Compounders can still make copycat weight loss drugs, but are losing their market advantage of widespread telehealth distribution and favorable pricing as brand-name GLP-1 prices decline , including for new pills

Together, these effects regulate blood sugar, reduce appetite, and support metabolic balance

doi: 10.1016/j.metabol.2021.154838 31 OppertJ-MCianguraCBellichaA

In summary, the relatively higher expression of GLP-1R on -cells allows GLP-1 to indirectly inhibit glucagon secretion by promoting somatostatin secretion

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The primary objective is to maximize gastric emptying delay and induce a massive caloric deficit
