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Topiramate, an anticonvulsant used off-label for weight management, produces modest weight loss by reducing appetite and increasing satiety
Diabetes Nutr Metab 17:336342 Yasuda N, Inoue T, Nagakura T et al (2002) Enhanced secretion of glucagon-like peptide 1 by biguanide compounds

Ro also provides access to branded weight loss drugs like Wegovy and Ozempic

Investigation 79 (2), 616619

It causes sudden, painless vision loss in one eye with irreparable damage to the nerve and impacts the eyes connection to the brain

As a result, researchers have sought new therapeutic strategies with different mechanisms of action to enhance T 2 DM management (12, 13)
