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Topiramate, an anticonvulsant used off-label for weight management, produces modest weight loss by reducing appetite and increasing satiety

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Diabetes Nutr Metab 17:336342 Yasuda N, Inoue T, Nagakura T et al (2002) Enhanced secretion of glucagon-like peptide 1 by biguanide compounds

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Investigation 79 (2), 616619

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It causes sudden, painless vision loss in one eye with irreparable damage to the nerve and impacts the eyes connection to the brain

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