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PBH pathophysiology implicates heightened insulin and glucagon-like peptide 1 (GLP-1) levels, with bile acids (BA) contributing to GLP-1 release
Belching is a frequent digestive side effect reported by people taking tirzepatide for weight loss
This paper provides a review on the current evidence supporting the use of GLP-1 in experimental animal models and human trials with the ischemic and non-ischemic heart and discusses their molecular mechanisms and potential as a new therapeutic approach.

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Retatrutide is a triple agonist (GIP/GLP-1/glucagon receptor) studied in advanced metabolic research applications