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If you take warfarin or other coumarin anticoagulants, more frequent INR monitoring is recommended when starting semaglutide

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GLP-1 receptors are also widely expressed in the central nervous system, including the brainstem, cerebellum, hippocampus, cortex, hypothalamus, and amygdala [7, 10, 11]

Beneficial effects of these agents have been noted in conference presentations and most recently for LY3537021, which is reported to induce significant weight loss in subjects with T2D but without nausea or vomiting [961], and NNC0480-0389, which in a phase 2 study in individuals with overweight/obesity and T2D enhanced weight loss relative to treatment with semaglutide 2.4 mg (EudraCT Number 2020-004863-14 - Clinical trial results - EU Clinical Trials Register)

Scientific References Prevalence and predictors of postoperative thiamine deficiency after vertical sleeve gastrectomy

Questions to Ask Yourself: Before pursuing any prescription weight loss peptides program, consider: Have I discussed weight management options with my primary care provider