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[1] [2] These include reduced caloric intake due to appetite suppression, gastrointestinal side effects leading to decreased food intake, delayed gastric emptying, changes in blood glucose levels, and the metabolic adjustments associated with significant weight loss

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However, this theory is mainly based on findings from some animal models

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While not approved to treat these conditions, in a clinical trial, people who dieted, exercised and took Zepbound for the treatment of obesity or overweight with weight-related medical problems observed changes in cholesterol and reductions in blood pressure and waist size