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[90] Endocrine effects may include suppression of the hypothalamic-pituitary-adrenal axis, which could lead to adrenal insufficiency if therapy is discontinued abruptly

[1] [2] Patients should also be alert to symptoms of gallbladder disease, such as right upper abdominal pain or jaundice

By this point, most patients have completed initial dose titration and are seeing consistent weekly loss

In 2021, the FDA approved these higher doses of semaglutide, under the brand name Wegovy, for weight loss

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If low or low-normal, use higher dose supplementation or injectable b12