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Lee SO, Kuthati Y, Huang WH, Wong CS (2024) Semaglutide Ameliorates Diabetic Neuropathic Pain by Inhibiting Neuroinflammation in the Spinal Cord

You might feel sick within hours of eating a meal

If this patient increases the dose to 15 mg (purple curve), then (a) increasing the dosing interval to 10 days reduces cost by 30% and maintains identical weight loss and (b) increasing the dosing interval to 14 days reduces cost by 50% and maintains 87% weight loss Figure 3D concerns a patient on 15 mg q1wk and shows that they can cut their costs in half and retain 79% of their weight loss

Of course, while cash-pay provides immediate revenue, the real juicy volume still comes through insurance

Which translates to bonking 1520 minutes earlier than baseline, or needing an extra 2436 hours to fully recover between hard sessions

Semaglutide, a GLP-1 receptor agonist originally developed for type 2 diabetes, has become one of the most prescribed medications for weight management