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NAION or sudden vision loss in one eye

12% in participants without T2D, 8% in participants with T2D), and standard deviations of 6% for placebo and 10% for survodutide were assumed, whereas participants with early treatment discontinuation were assumed to respond the same as those completing the trial on placebo

Appetite reduction is often the earliest noticeable effect, reported within the first one to two weeks due to GLP-1 activity on hypothalamic satiety signalling

Standard 2-year carcinogenicity studies in animals have not been performed to evaluate the carcinogenic potential of insulin degludec

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Semaglutide is still at lower titration doses, so appetite suppression effects are present but building