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Comparison of the effects of glucagon-like peptide-1-(1-37) and -(7-37) and glucagon on islet hormone release from isolated perfused canine and rat pancreases

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The key finding: tirzepatide, which produces the most weight loss (up to 22.5% body weight), was most frequently linked to telogen effluvium

The usual recommendations and guidance that would be given for initiation of a once-weekly GLP-1 receptor agonist should be provided (e.g., direction to take the medication once weekly, information on how to manage missed doses, device-specific instructions, mealtime considerations, appropriate timing for oral medications, storage instructions, and availability of programs supporting adherence) (63)