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On Wegovy (semaglutide for weight management)

Each type of fermentable fiber produces different ratios of butyrate, propionate, and acetateall of which activate L-cells through slightly different mechanisms

Importantly, formulations add further steps

This becomes particularly relevant in the context of GLP-1 receptor agonist therapy, where the substantial weight loss these medications produce is not exclusively fat loss

Semglee (insulin glargine biosimilar from Biocon/Viatris) received the first FDA interchangeability designation in 2021 [42]
(Abstract 57-OR) [Google Scholar] 48.Pratley RE, Nauck MA, Bailey T, et al
