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Clinicians need to be vigilant and exercise extreme caution as the emerging adverse event profile of this novel medication unfolds
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doi:10.1161/CIRCULATIONAHA.124.067676 9

It is an unapproved research chemical , not a medicine, and there are no completed human efficacy trials presented for research and educational use only

Acute electrical stimulation of pudendal sensory nerve at low intensity (0.0250.05 mA) resulted in an increase in voiding efficacy only in 8-week diabetic animals
Despite the antihistamine Benadryl not being impacted by the FDA committees vote, this isnt to say that OTC Benadryl isnt without controversy