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Patients may notice increased cold sensitivity in their extremities, a general feeling of being chilly even in comfortable environments, or difficulty staying warm compared to before starting treatment

As a limitation, the fact that both patients successfully desensitized with exenatide had non-anaphylactic immediate allergic reactions, leading to insufficient evidence for the application of this protocol in anaphylaxis

But this new drug class had the potential to treat a host of other problems

New clinical evidence is expanding the range of conditions GLP-1s may address

The primary outcomes analyzed were the mean differences in the change from baseline for the apnea-hypopnea index (AHI), body weight, and systolic and diastolic blood pressure

We have to start looking at this differently, she said