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Another way of action for gut-derived GLP-1 includes indirect signaling via the vagus nerve

40 Additionally, GLP-1RAs have been shown to have both cardio-protective and reno-protective effects 41 44 and the effects of withdrawal of these medications on peri-procedural morbidity is unknown

In T2DM: 0.49% after 13 hr, n=205

Critical care isnt about memorizing doses its about understanding physiology

Hyperglycaemia that is mechanistically distinct from the fibrosis-driven chronic pancreatitis model is the result of factors that promote insulin resistance in the liver and cell dysfunction, such as adrenomedullin and circulating exosomes

Even then, the mixed effects analyses did not reveal a significant durability of weight loss with longer durations of therapy
