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"SNAC-enabled oral peptide delivery: absorption mechanisms and clinical implications." Clinical Pharmacology in Drug Development
In that case, the medication was supposed to be frozen and thawed before use
Geerling et al., 2010 )
[DOI] [PMC free article] [PubMed] [Google Scholar] 560.Lyssenko V., Lupi R., Marchetti P., Del Guerra S., Orho-Melander M., Almgren P
It does not mean every patient must increase on this exact schedule
Not everyone experiences these uncomfortable symptoms, but those who do tend to feel them most severely when they step up to a higher dose of the medicine
