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For people who feel they've tried everything, this medication can be the tool that helps healthy habits finally stick

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist a medication that mimics the action of GLP-1, a naturally occurring hormone produced in the gut in response to eating

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In another study, GLP-1 and exendin-4 treatment was shown to normalize the altered vascular tone in type 2 diabetic rats, with the latter being less effective [115]

When to hold a dose instead of escalating The standard semaglutide dosing chart calls for monthly dose increases, but this is a guideline, not a mandate

For a 200-pound person, this translates to 24 to 30 pounds with semaglutide and 30 to 38 pounds with tirzepatide