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In addition, regulatory bodies are becoming more supportive of new therapies, which may further accelerate the approval process for GLP 1 analogues

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Common culprits include: Hot peppers Wasabi Horseradish Spicy soups Foods served at temperatures hot enough to make you question your life choices People with gustatory rhinitis often experience a runny nose along with sneezing

Common gastrointestinal effects reported with GLP-1 therapy include: Nausea (commonly reported, especially during dose escalation) Constipation or diarrhoea Abdominal discomfort or bloating Reduced appetite and early satiety Regarding bowel movement colour specifically, changes in stool colour are not listed as adverse effects in UK SmPCs for GLP-1 receptor agonists

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Alternative Pathways Weight loss from GLP-1 agonist therapy whether semaglutide, liraglutide, or tirzepatide can help many get down to a healthier weight, sometimes exhibiting losses of up to 20% of their starting weight