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For each study included in the review, we extracted detailed information on the study design, sample size, participant characteristics, type and dosage of GLP-1 RA used, and the key outcomes measured

If a 10mg/mL vial started with 5 mL and now has 2 mL remaining, it is still 10mg/mL

Related: Stopping GLP-1 Drugs Triggers Weight Regain 4x Faster Than Ending Exercise The trial was small just over 100 people in each group but it suggests a promising path: that weight loss achieved through these medications can be maintained in the long term, along with their wider health benefits, in a way that may also be more affordable

[PubMed: 4018423] 33

Randomized trials focused on efficacy and common adverse events but were not powered to detect rare thromboembolic events reliably

The connection to how GLP-1 medications affect energy levels is worth noting for migraine patients, since fatigue is both a common migraine prodrome and a reported early side effect of GLP-1 treatment, and distinguishing between the two during the adjustment period can be genuinely confusing