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November 1, 2023

Foods that support short-chain fatty acid production-When gut bacteria feed on dietary fibre, they produce postbiotics that contain short-chain fatty acids (SCFA) such as acetate and butyrate

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Stopping Ozempic triggers a gradual decline in its appetite-suppressing effects over 48 weeks, with most patients regaining lost weight within months without continued treatment

Here, the authors report cryo-EM structures of tirzepatide-bound GIPR and GLP-1R, peptide 20-bound GIPR, GLP-1R and GCGR, revealing the molecular basis of their multiplexed pharmacological actions.