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Which HRT delivery methods are affected Affected by GLP-1 medications (oral delivery): Oral estrogen tablets (conjugated equine estrogens, estradiol) Oral progesterone (micronized progesterone, such as Utrogestan) Oral progestins (norethisterone, medroxyprogesterone) Oral testosterone (testosterone undecanoate) NOT affected by GLP-1 medications (non-oral delivery): Transdermal estrogen patches Topical estrogen gels and creams Vaginal estrogen rings or suppositories Progesterone-releasing IUD (Mirena) Transvaginal progesterone Testosterone injections Testosterone pellets Testosterone patches or gels The distinction is simple

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Research from 2023 found that people lost Two popular GLP-1 medications, Ozempic and Mounjaro (tirzepatide), only have FDA approval for the management of type 2 diabetes

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Nobody could have predicted the vogue for GLP-1 drugs, which were originally designed to treat Type 2 diabetes