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Their widespread use for diabetes, obesity, and cardiometabolic health has naturally drawn attention far beyond their original indications
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When the blood glucose level is high, pancreatic cells secrete insulin to reduce blood glucose levels, which is facilitated by incretins secreted by the gastrointestinal tract

Marx N, Davies MJ, Grant PJ et al

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For the last several years, the focus has shifted from growth-at-all-costs to durability, profitability, and clinical-grade evidence
